Detalhe da pesquisa
1.
Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy.
Cell
; 175(3): 766-779.e17, 2018 10 18.
Artigo
Inglês
| MEDLINE | ID: mdl-30340042
2.
BMAL1 drives muscle repair through control of hypoxic NAD+ regeneration in satellite cells.
Genes Dev
; 36(3-4): 149-166, 2022 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35115380
3.
SPT5 stabilization of promoter-proximal RNA polymerase II.
Mol Cell
; 81(21): 4413-4424.e5, 2021 11 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34480849
4.
Acute perturbation strategies in interrogating RNA polymerase II elongation factor function in gene expression.
Genes Dev
; 35(3-4): 273-285, 2021 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33446572
5.
A trivalent nucleosome interaction by PHIP/BRWD2 is disrupted in neurodevelopmental disorders and cancer.
Genes Dev
; 35(23-24): 1642-1656, 2021 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34819353
6.
Chromatin Hyperacetylation Impacts Chromosome Folding by Forming a Nuclear Subcompartment.
Mol Cell
; 78(1): 112-126.e12, 2020 04 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32243828
7.
NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release.
Mol Cell
; 78(2): 261-274.e5, 2020 04 16.
Artigo
Inglês
| MEDLINE | ID: mdl-32155413
8.
A small UTX stabilization domain of Trr is conserved within mammalian MLL3-4/COMPASS and is sufficient to rescue loss of viability in null animals.
Genes Dev
; 34(21-22): 1493-1502, 2020 11 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33033055
9.
Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia.
Genes Dev
; 33(1-2): 61-74, 2019 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30573454
10.
A synthetic lethality screen reveals ING5 as a genetic dependency of catalytically dead Set1A/COMPASS in mouse embryonic stem cells.
Proc Natl Acad Sci U S A
; 119(19): e2118385119, 2022 05 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35500115
11.
Histone H3K4 methylation-dependent and -independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation.
Genes Dev
; 31(17): 1732-1737, 2017 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28939616
12.
SET1A/COMPASS and shadow enhancers in the regulation of homeotic gene expression.
Genes Dev
; 31(8): 787-801, 2017 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28487406
13.
A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation.
Genes Dev
; 31(19): 2003-2014, 2017 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29089422
14.
DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation.
Proc Natl Acad Sci U S A
; 117(44): 27365-27373, 2020 11 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33077595
15.
Therapeutic targeting of transcriptional elongation in diffuse intrinsic pontine glioma.
Neuro Oncol
; 23(8): 1348-1359, 2021 08 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33471107
16.
Coordinated regulation of cellular identity-associated H3K4me3 breadth by the COMPASS family.
Sci Adv
; 6(26): eaaz4764, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32637595
17.
Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation.
Nat Genet
; 52(6): 615-625, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32393859
18.
Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia.
Cancer Discov
; 10(9): 1388-1409, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32444465
19.
CATACOMB: An endogenous inducible gene that antagonizes H3K27 methylation activity of Polycomb repressive complex 2 via an H3K27M-like mechanism.
Sci Adv
; 5(7): eaax2887, 2019 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31281901
20.
USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia.
Clin Cancer Res
; 25(1): 222-239, 2019 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30224337